KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K3
All Species:
25.76
Human Site:
T98
Identified Species:
47.22
UniProt:
P46734
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46734
NP_002747.2
347
39318
T98
A
V
K
R
I
R
A
T
V
N
S
Q
E
Q
K
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
E102
A
R
K
L
I
H
L
E
I
K
P
A
I
R
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546666
347
39324
T98
A
V
K
R
I
R
A
T
V
N
S
Q
E
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
O09110
347
39278
T98
A
V
K
R
I
R
A
T
V
N
T
Q
E
Q
K
Rat
Rattus norvegicus
Q4KSH7
419
47517
S154
A
V
K
Q
M
R
R
S
G
N
K
E
E
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511595
352
40240
T103
A
V
K
R
I
R
A
T
V
N
T
Q
E
Q
K
Chicken
Gallus gallus
Q90891
398
44059
E104
A
R
K
L
I
H
L
E
I
K
P
A
I
R
N
Frog
Xenopus laevis
Q07192
446
50082
T183
A
V
K
R
I
R
S
T
V
D
E
K
E
Q
K
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
T114
A
V
K
R
I
R
A
T
V
N
T
Q
E
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477162
334
38176
L93
Q
H
R
L
V
M
D
L
D
I
S
M
R
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
N100
A
V
K
R
I
R
C
N
N
I
G
H
R
E
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJV0
356
39818
N104
A
M
K
V
I
Q
M
N
I
Q
E
E
I
R
K
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
E394
A
T
K
E
V
R
L
E
L
D
E
A
K
F
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.7
N.A.
99.1
N.A.
96.5
37.2
N.A.
89.7
30.3
42.1
75.3
N.A.
57
N.A.
37.7
N.A.
Protein Similarity:
100
47
N.A.
99.7
N.A.
98.8
56.7
N.A.
93.1
48.7
58
84.4
N.A.
72.9
N.A.
55.6
N.A.
P-Site Identity:
100
20
N.A.
100
N.A.
93.3
46.6
N.A.
93.3
20
73.3
93.3
N.A.
6.6
N.A.
40
N.A.
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
73.3
N.A.
100
33.3
93.3
100
N.A.
20
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
93
0
0
0
0
0
39
0
0
0
0
24
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
16
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
24
0
0
24
16
54
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
16
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
77
0
0
0
24
16
0
0
24
0
0
% I
% Lys:
0
0
93
0
0
0
0
0
0
16
8
8
8
0
62
% K
% Leu:
0
0
0
24
0
0
24
8
8
0
0
0
0
0
0
% L
% Met:
0
8
0
0
8
8
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
16
8
47
0
0
0
8
16
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% P
% Gln:
8
0
0
8
0
8
0
0
0
8
0
39
0
47
8
% Q
% Arg:
0
16
8
54
0
70
8
0
0
0
0
0
16
24
8
% R
% Ser:
0
0
0
0
0
0
8
8
0
0
24
0
0
8
8
% S
% Thr:
0
8
0
0
0
0
0
47
0
0
24
0
0
0
0
% T
% Val:
0
62
0
8
16
0
0
0
47
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _